Hormones & Signal Transduction — Practice

Question 1

Which second messengers are generated by Gq-coupled receptor activation?

Accepted Answer

C

Question 2

A hormone produces its effect within seconds. Which receptor family can be excluded?

Accepted Answer

C

Question 3

Cholera toxin causes profuse watery diarrhoea by which mechanism?

Accepted Answer

B

Question 4

Growth hormone and prolactin signal through which pathway?

Accepted Answer

C

Question 5

Why is co-administration of a nitrate and sildenafil contraindicated?

Accepted Answer

B

Question 6

A patient has hypocalcaemia, hyperphosphataemia and a markedly RAISED parathyroid hormone level, with short fourth metacarpals. What is the defect?

Accepted Answer

C

Question 7

Why does continuous GnRH agonist therapy suppress gonadotropin secretion while endogenous pulsatile GnRH stimulates it?

Accepted Answer

B

Question 8

In insulin resistance, glucose uptake is impaired while growth-promoting effects such as acanthosis nigricans persist. What explains this?

Accepted Answer

B

Question 9

Tamoxifen antagonises the oestrogen receptor in breast tissue but acts as a partial agonist in endometrium. What mechanism explains this?

Accepted Answer

A

Practice — Hormones & Signal Transduction