Immunopathology & IHC Markers — Practice

Question 1

A tuberculin skin test is read at 48 to 72 hours. Which hypersensitivity type does it represent?

Accepted Answer

D

Question 2

Which immunohistochemical marker most specifically identifies a gastrointestinal stromal tumour?

Accepted Answer

B

Question 3

A patient develops fever, urticaria, arthralgia and haematuria ten days after receiving equine antivenom. Complement levels are low. Which mechanism is responsible?

Accepted Answer

C

Question 4

A boy has recurrent bacterial infections. Serum IgM is raised, while IgG, IgA and IgE are all very low. B cells are present. What is the defect?

Accepted Answer

B

Question 5

A woman with a connective tissue disease is planning pregnancy. Which antibody most warrants checking because of a specific fetal risk?

Accepted Answer

C

Question 6

A supraclavicular node biopsy shows metastatic carcinoma that is cytokeratin positive, TTF-1 positive, CDX2 negative and PSA negative. What is the most likely primary?

Accepted Answer

C

Question 7

A renal allograft becomes mottled and fails to perfuse within minutes of vascular anastomosis. What is the mechanism?

Accepted Answer

A

Question 8

A young adult has had two separate episodes of meningococcal meningitis. Immunoglobulins, neutrophil count and T cell subsets are all normal. What should be tested?

Accepted Answer

B

Question 9

A patient develops arthralgia, rash and a positive antinuclear antibody after several months of hydralazine. Anti-histone antibody is positive and anti-double-stranded DNA is negative. Which feature is most expected?

Accepted Answer

B

Practice — Immunopathology & IHC Markers

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